Antibacterial Agent

Antibacterial Agent

Formic acid, also known as formic acid, is an organic acid with the simplest structure and has excellent antibacterial ability. However, its strong pungent odor and corrosiveness limit its single application in production, and it is usually compounded with other acidulants or processed into organic acid salts. With the advancement of science and technology, safe and non-irritating formic acid derivatives have been developed, including formates, benzoic acid and its salts, and potassium diformate. Compared with formic acid, calcium formate overcomes its irritation, corrosiveness and instability, and broaden the scope of application of formic acid acidulants.
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Calcium formate is an excellent antibacterial agent.

feed grade calcium formate 2

 

Calcium formate is a new type of feed additive that serves as both an acidifier and a calcium source. Its water-soluble properties maintain the stability of nutrients in the feed and do not cause the loss of nutrients such as amino acids and vitamins. Calcium formate is stable and not easy to decompose. It is non-irritating and non-corrosive. It is widely used in all kinds of animal feed as an acidifier, mildew preventer, and antibacterial agent. In China, calcium formate was approved as a preservative and mildew preventer in 2013; in 2014, the European Union approved its use as a feed preservative, and in 2018 it was approved as a feed additive for broilers and laying hens; in 2020, the United States allowed it to be used as an acidifier for pig and chicken feed.
 

feed grade potassium diformate

 

Benzoic acid, due to its highly lipophilic molecular structure, can interfere with the bacterial cell membrane structure or enter the cell to inhibit bacterial growth, showing a wide range of antibacterial effects. In 2003, Europe allowed the addition of no more than 1% benzoic acid as an acidifier in pig feed, and further approved its use in broiler and laying hen feed in 2018. However, benzoic acid is poorly water-soluble and has a formaldehyde odor, which may affect the animal's feed intake.

Potassium diformate, as an EU-approved feed additive to replace antibiotics, has been allowed to be used in pig feed since 2001, and was further approved for use in sow feed in 2005. In 2005, the Ministry of Agriculture and Rural Affairs of China also approved the use of potassium diformate in pig feed. As a non-antibiotic feed additive, potassium diformate has the advantages of being green, residue-free, low corrosive, and low irritant. Slowly released in the animal digestive tract, it can not only play the role of formic acid, but also utilize the characteristics of potassium formate to effectively regulate the pH value of the animal gastrointestinal tract, improve intestinal flora, and promote the digestion and absorption of nutrients.

 

 

In summary, formic acid and its derivatives play an important role in feed antibacterial preservation, animal intestinal acidification, and animal growth promotion, and have become an indispensable component of feed acidifiers. With the continuous advancement of science and technology, the derivatives of these organic acids have been continuously optimized, providing a strong guarantee for animal health and food safety.

 

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