Sodium Formate 98% Min

Sodium Formate 98% Min

Sodium formate 98% has always played a key role in pharmaceutical manufacturing and has been widely used. What are the specific applications of sodium formate 98% in the pharmaceutical industry? What specific drug ingredients are particularly important for sodium formate 98% to synthesize? Below is a detailed introduction and answer. Let us get to know the function of sodium formate in the pharmaceutical field.
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sodium formate 98%

 

 

Product Features

High purity
The purity of sodium formate is not less than 98%, and the impurity content is low. Among them, the impurity content of impurities and water-insoluble substances is controlled within 0.5%, which can effectively improve the conversion rate and product quality of industrial reactions.

 

Rapid dissolution
Sodium formate with a purity of more than 98% is in the form of dry granules or powders. The particles are small and evenly distributed, and the dissolution time in room temperature water is less than 60 seconds.

 

Long storage time
The product is vacuum dried, and the moisture content is controlled below 1%. It is not easy to absorb moisture and agglomerate. It can be stably stored for 12 months under normal storage conditions without discoloration or crystallization.

 

sodium formate 2

 

 

 

sodium formate 98

 

 

The key applications of 98% sodium formate in the synthesis of specific drug ingredients are as follows:

 

In the synthesis of the antiviral drug sodium foscarnet, the Arbuzov method can be used to condense diethyl phosphite or triethyl ester with ethyl chloroformate, and then undergo alkaline hydrolysis to synthesize sodium foscarnet. This drug has a broad-spectrum antiviral effect and is relatively low in toxicity.

 

In terms of anti-infective drugs, 98% sodium formate can significantly increase the sensitivity of bacteria to antibiotics, making antibiotics that were originally ineffective or ineffective against pathogenic bacteria effective or even efficient, thereby killing bacteria and achieving the purpose of anti-infection. In particular, when it is used in combination with aminoglycoside antibiotics (such as minomycin, gentamicin, amikacin, etc.), it can play a synergistic role and can effectively kill bacteria even at low antibiotic concentrations, achieving better anti-infection effects.

 

In the production of formic acid and oxalic acid, 98% sodium formate will produce sodium oxalate after dehydrogenation. Sodium oxalate is treated with lead sulfate and then acidified with sulfuric acid to obtain oxalic acid. Oxalic acid can be used in the pharmaceutical industry to produce drugs such as antibiotics and borneol, and can also be used to synthesize various oxalates, oxalates and oxalamides.

 

 

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